B- Blocker contraindications, cuation mnemonics

1, B- blocker Contraindications mnemonics

    Main contraindications and cautions:

A = Asthma ( Bronchial Asthma),
       ACS
B = Block i.e. Partial or Complete Heart block ( Especially propanolol )
       Bradycardia
C = COPD
       Congestive heart failure ( CHF ), LVF
D = Diabetes Mellitus
E = Electrolyte Disturbances i.e Hyperkalemia(K+ excess)
F = Fluid retention ( Massive fluid retention, who need vasodilators or inotropic drugs )
G
H = Hyperlipidemia ( Specially nonselective B-blocker, e.g. propanolol= Raise TG, LDL and reduce HDL )


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Propanolol


Non selective B-blocker(β1+β2)

Cardioselective B-blocker (β1)

β2 selective blocker

Adrenergic β2 Stimulation ----> Stimulates β cell adenylyl cyclase----> Increases Insulin secretion---> Hypoglycemia.[Hence CI in DM patients under medication due to risk of hypoglycemia]